Some countries are planning to wait up to 12 weeks to administer second doses of COVID-19 vaccines. Will this slow the virus?
CoVID-19 News & Updates playlist: alfirst.info/one/PLsNB4peY6C6IQediwz2GzMTNvm_dMzr47.html
Hosted by: Hank Green
SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at www.scishowtangents.org
----------
Support SciShow by becoming a patron on Patreon: www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Silas Emrys, Jb Taishoff, Bd_Tmprd, Harrison Mills, Jeffrey Mckishen, James Knight, Christoph Schwanke, Jacob, Matt Curls, Sam Buck, Christopher R Boucher, Eric Jensen, Lehel Kovacs, Adam Brainard, Greg, Ash, Sam Lutfi, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, charles george, Alex Hackman, Chris Peters, Kevin Bealer
----------
Looking for SciShow elsewhere on the internet?
Facebook: scishow
Twitter: scishow
Tumblr: scishow.tumblr.com
Instagram: thescishow
----------
Read more about the ethics of altered vaccine schedules:
blog.petrieflom.law.harvard.edu/2021/01/06/covid-vaccine-one-dose-two/
www.cdc.gov/mmwr/volumes/69/wr/mm6947e3.htm#contribAff
Sources:
www.sciencemag.org/news/2021/01/could-too-much-time-between-doses-drive-coronavirus-outwit-vaccines
www.cdc.gov/vaccines/hcp/conversations/downloads/vacsafe-understand-color-office.pdf
www.bmj.com/content/372/bmj.n18
news.ncsu.edu/2021/01/one-dose-or-two/
www.bbc.com/future/article/20210114-covid-19-how-effective-is-a-single-vaccine-dose
www.immunology.org/policy-and-public-affairs/briefings-and-position-statements/COVID-19-vaccine-dosing-schedules www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32661-1/fulltext
www.nejm.org/doi/10.1056/NEJMoa2034577
www.reuters.com/article/us-health-coronavirus-germany-biontech/biontech-says-no-data-to-support-delayed-vaccine-booster-shot-idUSKBN2991XX
blogs.bmj.com/bmj/2021/01/05/covid-19-vaccines-to-delay-or-not-to-delay-second-doses/
www.theguardian.com/world/2021/jan/04/germany-denmark-second-dose-covid-vaccine
www.fda.gov/news-events/press-announcements/fda-statement-following-authorized-dosing-schedules-covid-19-vaccines
Why Some Countries Are Delaying COVID Booster Shots
1 446 Shikime 147 mijë
We referred to the second dose in a vaccine series as a "booster." That's fine in everyday terms, but we wanted to clarify that doctors generally refer to two doses of a vaccine given a few weeks apart as the "primary series," and shots given to bolster immunity later as "boosters." So if you've heard it differently, that's why! We'll go into the difference a little bit more in an upcoming episode.
Why all of a sudden all these changes? Extending the time between doses??? Mix-matching doses??? The testing was rushed to begin with...now all these changes totally make these vaccines unreliable... What would cause them to do these changes mid-stream?!?! Just read the script and cash the checks!
It is safer not to touch the vaccines at all .
The data so far is pointing to that it was a gamble that has paid off. Data from Israel and the UK shows this response to be working well. One of the few things the UK has actually gotten right.
I'm still pissed about this weeks later. We can't conduct unethical, country-wide experiments. This cannot be an option in the 21st century... or ever.
yeah, about that "study" in Israel. Do people know that this is a study being done on the entire population of the country? The government entered into an agreement with Pfizer to exchange it's citizens personal medical information for an undisclosed amount of money or vaccines. The date they made the agreement has not been disclosed as well as any liabilities if the experiment goes wrong. this agreement was made without the agreement of its citizens to participate. it came to light and they were forced to publish it though many important parts were redacted. Now that the nations vaccine drive has slowed down, the government is resorting to some pretty frightening tactics to coerce its public to vaccinate. Including ordering the ministry of health to release name phone and addresses of unvaccinated individuals to local agencies who are authorized to "convince" these people to vaccinate. So much for medical privacy. It's very interesting for me to see the nightmare playing out before my eyes in Israel, so casually referred to as a "study".
I'm not scared of the vaccin, but i do fear the abuse coming from governments and the lack of transparency. With environnemental issues and the fear of diseases that was created along side the pandemic, the futur isn't bright for the next generations
Lockdowns, face coverings and shutting schools are not proven by science either, however still enforced on the UK population
@Real Human Exactly the same here. When the lockdown wasn't working Matt Hancock would say at the daily briefing "It's people flexing and not following the rules".
Québec too, and when something doesn't work, the minister blame the population. He hasn't take any responsibilities for the choices he made
There must be extremely solid supporting theory. Heath regulators aren’t gamblers.
When calulated in a more logical way the effectiveness of the 2 main vaccines in the west, with the first dose, is very high (80 to 90 per cent). To date that level has been maintained for at least 9 weeks (may be 10 weeks at 22-02-21) and this level will not suddenly drop off rapidly after the 10th week. Admittedly it was a bit of a gamble but it looks like it is paying off. Already in some parts of the UK the first shots have reduced hospitalisation by 90 per cent. Hope the programme continues to be successful. Get the jab.
Science vs politics ...again!?
Get you vaccines covid junkies. Shilling for the nwo.
If you believe in evolution then we are actually made up from those infectious diseases (bacteria, fungi, viruses) we are tricked into fearing. They are symbiotic to our cells and minerals. Psychological warfare works on stupid people who fear death and are afraid to live life. You turned people into a bunch of OCD freaks!! Go debunk all your past videos you made ya money hoarding greedy dumb asses.
got my second pfizer shot after 27 days!
....i will take my chances on this one!
Sputnik V has two different antigens in the two shots.
This seems like a poor decision.
This is so typical. Every body is an expert but nobody really knows what the facts are.
They need to spread them out further so as Not to attract the massive amounts of deaths and/or harmful effects these (Not vaccines) are causing. It's drawing too much attention.
I got super downvoted on reddit for even suggesting that experts should estimate whether we might approach herd immunity faster if we focus on distributing first shots and slow down with the boosters for now. I wasn't saying that was the answer, just that I was wondering if the experts were exploring the idea. I think people forget that herd immunity is the goal. We need ALL of our grandma's protected, not just a few of them. Not saying I have the answer though. The science just isn't there yet, so it's a pretty big gamble.
The answer is no it’s probably not worth the risk until/unless testing has been done
Scientists: "We can't say we know something If it hasn't been tested" MDs: Lol hold my pride and watch me
None of these "vaccines," not one, were tested on individuals who actually had already contracted Covid-19. And my virologists now believe such individuals will only need one shot (at most) to have the same level of resistance...
then why the FRICK is Canada delaying the 2 doses by >6 weeks ??? if it may? not even? work?
The left says follow the science until it doesn''''''t fit their donors or masters wishes. They listen to CDC when it is politically expedient.
And this is what causes people to lose trust and blame the vaccines and scientists when it's actually higher ups doing greedy, shady things that cause all this distrust. Doesn't matter if the vaccine works and the science is sound if politicians decide people don't need to recieve them in the necessary dose or time period. It's so frustrating.
Not getting the vaccine. My immune system is all I need. Strength your immune systems folks.
Yeah, I don't see how it is at all ethical to test mixtures of vaccines without the consent and knowledge of the participant.
Wait... couldn't spreading the dosage out over such a long period be harmful? We really don't need this virus mutating, but won't this apply selective pressure to get better at infecting us?
... the introvert in me just heard we're going to have many more years of Corona and more antibiotic-resistant strains and is just trying to pretend it's not happy about this. The extrovert in me is crying.
Yeah, tbh I will not be very surprised if things go sideways - messing with the correct way a vaccination should be done just sounds like cutting corners where they shouldn't be cut.
How about just forgetting the vaccines and eliminate Covid-19 by all of us taking Ivermectin as a prophylactic measure all at the same time...? Enough information is out there now that pretty much proves that Ivermectin will eradicate Covid-19 in a body; so if we all take it at the same time; we could theoretically starve out COVID-19 permanently. And potential bonus; because of the genetic similarity between COVID-19 and the common cold and flu; we might just wipe them out too.
Prophylactic use of antimicrobial agents are dangerous as it will give rise to superbugs. Vaccines are easy to make compared to drugs. Ivermectin before it is an agent used to tread covid-19, it is a potent antifungal agent. Thus, by exposing large population as prophylaxis allows organism to develop resistance. Plus, like for vaccines there are contraindication for ivermectin. In case of vaccine, herd immunity is to protect those who can't be vaccinated but in a prophylactic use that plan will fail because you can never give same drug to everyone and without inducing any immunity the same person will be infected from the person who did not take the drug in the 1st place.
There is another point that this video missed, there is data from the trials that say that having one dose reduces risk of hospitalisation and death therefore this decision was made to help the NHS which was at the time at breaking point due to the new variant, it is still under extreme pressure now even when the hospitalisations are falling daily. I'd rather us to stick to the schedule but it was a decision that needed to be made.
As the scripture says: Whosoever shall seek to save his life shall lose it; and whosoever shall lose his life shall preserve it. Luke 17:33 KJV Many will take covid-19 vaccine thinking they are saving themselves but the truth is they will be doomed forever. WAIT AND SEE!!!, LET HE WHO HAS EARS HEAR FROM THE LORD!!!!..!!!
Hail satan
I think when people are given their first dose the NHS should have rules in place to give people their second dose and rather than leaving it until the end to then say "sorry we gave your second dose to someone else as their first dose" just seems daft
We are already taking some calculated risk on rushed out vaccines, which is OK. But issueing a test protocol on an emergency protocol is exactly what Hank said: a gamble. The resoning behind the emergency was already developed. Further stretch of It is neither scientific, nor ethical.
“Peek under the hood” felt more like an Aranda line than a Hank one.
My doctor when getting the vaccine told me to act as though I had no immunity until enough of the population had BOTH jabs. If were being socially responsible enough to opt into the vaccine, we should be socially responsible enough to help protects it validity.
This makes me wonder if we're gonna need 3rd shots, a 4th, a 5th, etc.
I'm going to sound stupid, but the immune system is just mind boggling.
I'm immunocompromised and got my first dose of the Oxford-Astrazenica this week (in the UK). If they'd stuck to the recommended dosage scheme I wouldn't have had it yet. Honestly, I am happy they've made this decision - I'm still shielding, but now I'm slightly more protected if my partner gets infected whilst getting groceries or whatever. Obviously we're being careful but these things can and do happen. I'd rather have a chance at not dying from this thing sooner than later (because it could literally kill me), and if that means that I have to have an extra dose down the line because the science has changed or they have needed to make changes to make it more effective against new variants - that's OK too. I would rather that more people get however much protection one dose affords than a very small amount of people get the full 2 dose schedule but leaving vulnerable people completely unprotected. If the worst happens and we completely run out of supplies we'll have given more people a chance to not need hospitalisation even if they catch it and right now that's better for our strained hospitals and for people like me who have been terrified of catching this disease since last March. There is some science to support the decision, especially with the recent news that the Ox-Az vaccine may also help reduce transmission. I'm no Tory lover, and very much think they've ballsed up every decision they've made since the start of the pandemic but in this, I actually think they may have done the right thing.
Luciferase (I think that's how you spell it) I heard that it's in the shot --- I'll pass. * Given their "world population control" agenda, I trust my immune system, & ultimately God, more than them.
The abnormal gemini initially match because parcel hisologically peep with a straight jaguar. abaft, beautiful asphalt
Booster shots? Germany is not even getting first shots down all that fast. I got a letter in the mail essentially telling me I won't be getting vaccinated any time soon despite working in contact with different people daily at work. Yay.
Either way it doesn't matter unless mask usage and social distancing are actually practiced. The vaccine alone is not going to stop the pandemic.
If this guy was handcuffed, he couldn't talk.
what were they thinking??? better keep on the safe side it's literally a pandemic
yeahhhh boiiii can't wait for people to only get one shot and then think they're okay but they're really not and so the virus spreads ~even more~
Yet another public health organization chooses to shape regulations to match politics rather than data. At least it's not as bad as the time the WHO ignored valuable data on covid because it came from a country China doesn't like.
Explanation is always clear. Wonderful! 👍👍👍
Why is the UK delaying the vaccine? because our government is chaotic, disorganized, lazy, incompetent and practically criminally negligent. Their first tactic was to go for "crowd immunity" despite all evidence suggesting this would lead to a huge number of deaths. Our prime minister didn't go to government meetings surrounding Covid-19. When the scientific advisory board was giving advice he didn't like he secretly placed Dominic Cummings on said board. Our "World beating" track and trace system costing an estimated 22 billion pounds was heavily delayed and initially only managed to track an outbreak in its own call center, it still doesn't work, only managing to reach about 60% of contacts. Following our first national lockdown the government encouraged people to pack into restaurants with a "eat out to help out" scheme, offering discounts for meals to anybody eating IN a restaurant. Their care home policy has been described as "one of the most egregious and devastating policy failures of recent times" by the High court. They purchased PPE to the tune of £225 million, which was faulty and not fit for purpose, the owner of the company turned out to be a large financial contributor to the Tory party. The list just goes on and on, far longer than I want to put into a comment on an only vaguely related video, this comment is already long enough. Oh, and one last thing, don't forget to sing happy birthday while you wash your hands.
I had covid in March 2020, I had my first Oxford Astra Zeneca shot last week. I don't want to get it again or any of the new variants going around in UK. Nor do I want to be able give it to others. Even a "mild case" is no fun at all! So any needle phobes, bite the bullet and get your shot when you'r told!
Does even "effectiveness" have a standardized meaning? I have listened to an expert saying you can't really compare vaccines based od reports because once it was defined as presence of certain level of antibodies and once as developing symptoms of illness.
Really good point on the Ethics matter. But ... people are dying. Like the clinical trials, I think its worth the risk of doing the 'experiment' and the research in parallel. We are far from being in a 'comfortable setting'.
This is the kind of “vaccine skepticism” we need!: “Is it safe to use vaccines in ways that weren’t recommended?” not the “Are vaccines even safe at all?” mindset that most self-proclaimed “skeptics” use.
No, we need both. There is always a need for skepticism of anything, especially in science. The difference is that currently we have data to show to people who are wondering if the vaccines are safe that they ARE safe, where the answer to whether it's safe to use vaccines in ways that weren't tested (paraphrasing) is literally that we don't know because they weren't tested. The only type of skepticism we don't need is the skepticism that, in the face of clear evidence, only doubles down instead of softening and accepting that what is stated as truth may actually be truth.
so the uk and us are playing with everyone's lives
This is fine. Most of the work is done on the first shot. Pfizer gives a massive immune response from both killer t cells, and b cells (for antibodies) whereas parts of viruses or dead virus shots have very little immune response and need a lot more shots.
this is frigging bulldoody and amounts to a live test using the public as lab rats, and will further decrease their confidence in the vaccine even if no one dies. the latest in a whole series a of ill advised decisions taken by the Boorish Johnson govt, and one of the worst yet
Interesting topic, Québec is also adopting the same strategy as Britain.
I did the Sputnik Vaccine today, I am feeling okay, my friend has mild fever but we are well and please take the shots !
When we reach 4:50, we realize that it's all been noise up until that point (i.e., 30% "effective" for who-knows-how-long OR 50% "effective" for who-knows-how-long OR 90% "effective" for who-knows-how-long = 100% Quatsch raised to the third power). And after 4:50? I'm done.
We are in the U.K and my mum just receive the 1st Pfizer vax. Then found out it would be 12 weeks till the second. She is furious and believes they are breaking the consent agreement she signed. She believes she gave consent for a clinically tested vax AND schedule and what they are doing now by delaying the booster should be illegal. I agree with her! There is NO DATA on what they are doing so she IS a guinea pig. NOT what she signed consent for.
Remember the H1N1 virus during obama's term? It killed many more people than this plandemic. No masks were worn and it was china's fault. The plandemic requires a mask (which doesn't help at all) and it is Trump's fault. Any death whatsoever is being charged as covid. Biggest scam in the history of the world. It's all about control. Before you take a shot, ask them what's in it.
3:50 That map of Israel be lookin' G E N O C I D A L ...
Odd they excluded the Gaza strip, but included the West Bank and the Golan Heights. The Golan heights are sort of internationally accepted these days, but is new, and means this is not somekind of historic map. What kind of Israeli right wing group made that weird map?
It's not always the case that this is on governments/politicians - In Canada's case both Pfizer and Moderna have decided not to send us shipments on the schedule they originally told our government they would.
Whhhyyyyyyyy!!?!?!?? Good god! Just follow the damn instructions, Politicians. Stop trying to “wing it”, just stop it. 😭
No.
This video completely misses the key argument behind the gap used by the UK government - interrupting population spread. A thousand people being 50% protected is more effective than five-hundred people being 100% protected at decreasing the overall death rate. This is because it is more effective at dropping the R rate according to models. If you can interrupt community spread, the situation becomes less urgent. - (For the record, I'm not saying 50% and 100% are accurate figures, just that they exemplify the dynamic)
I’m really not into this kind of gamble, I’d rather keep masking and social distancing while enough vaccines are produced to vaccinate everyone on the recommended schedule.
Fortunately I already have my second moderna dose scheduled. It ended up being exactly 28 days. I feel guilty about this even though it’s just pure luck. Prayers go out that everyone wanting this vaccine get it 🙏
question, if i got covid and then a few weeks later after recovery i got the vaccine's first dose... is that similar to getting the vaccine and its booster?
33% effectiveness is worse than 95% effectiveness for half the population size
I was hoping you would spend time covering the risk benefit of an approach with a single dose and delayed second. From what i understand it's mostly to take pressure of the health services as it seem very likely that it will significantly reduce the number of critically ill Covid patients. It also seems in the UK that the most vulnerable are still reviving their second does in the vaccine producers advised window.
As someone who lives in the UK - am really unhappy with the government's decision to delay the second dose. It's an act of desperation by politicians who have never 'followed the science' like they claim! The rest of the world will seriously hate the UK if we manage to breed a vaccine resistant Covid strain...
UK politicians? Guranteed to eff this up
big issue is....if mixing fails to provide the anticipated effect and even harms people the anti-vaccine lobby will have a big gain in followers very quickly...
World-first COVID-19 alternating dose vaccine study launches in UK The study will examine whether different vaccines can safely be used for 2-dose regimes in the future. www.gov.uk/government/news/world-first-covid-19-alternating-dose-vaccine-study-launches-in-uk?
I understand why a government might take this gamble, but they insist they are 'following the science' which is obviously false and therefore doesn't give me any confidence in them.
It has nothing to do with with politicians selling vaccinnes off to Dubai I'm sure.
Scientists: "The vaccines are ready to be used! We've tested them and all you have to do is this!" Governments of the world: "Ehhhh, yeaaah, but we're just gonna space them out by 4 times as long and hey, why not mix a lil of this one with a bit of that one." Scientists: "WHAT?! NO NO NO!! Thats NOT how we tested them!"
I think this video does a very poor job of describing the reasoning why first-doses-first has been gaining acceptance. It seems like it is a fair and balanced description of the issues, but essentially amounts to a straw-man since the strongest arguments in favor of first-doses-first are not given. This article in Financial Times gives a better showcase of arguments in favor of first-doses-first. www.ft.com/content/915756b2-6f13-41fb-9491-a647817aa919 The reason that this approach is being used is that people who have run the numbers show that even with pessimistic views of the efficacy of the first dose, the overall loss of life in populations are reduced by immunizing as many people as possible as quickly as possible. There are very good population epidemiological reasons to give 2X the people "first doses first" and then follow up as quickly as possible with 2nd doses.
"Worth the risk" what risk, we can't sue anyone if anything goes wrong ?
Just two days after this we learned that a) vaccines do suppress spread of the virus , not just control the symptoms b) there is hardly any fall off in anitbodies until 90 days post the first dose.
3:48 that is map of Palestine, not Israel.
I was going to say that it was spectacularly unprofessional (and dangerous) for a science channel with such a broad following expected to give unbiased information to use that map.
The real use of data is to keep the public compliant so that they can make more money. If data does not support the business plan then it should not be considered
I do work in the healthcare sector and have been offered multiple times to talk the vaccine. However, I'm very skeptical of these vaccines that have been developed in such a short span of time under unique circumstances. Could you please cover the typical vaccine developmental method and compare it to the Covid vaccines developments?
They did. Unfortunately I cannot find it right now.
You'd think after everything that happened last year, politicians would be more willing to listen to scientists' unmitigated advice and not jump at the first chance to cock things up every step of the way. Sure, why not gamble vaccine doses and peoples' lives to maybe speed things up slightly and save a couple bucks? What's the worst that could happen?
Changing the schedule like that is also like conducting an experiment without the consent of the test subjects. Trial participants signed up to be guinea pigs; the rest of us did not.
hey arent you that old tik tok guy..... jk been on here for around a decade just saw you tik tok
I got my 2nd dose of the Pfizer Biontech vaccine yesterday, exactly after 3 weeks. While my reaction to the first one was surprisingly mild, the second one is much stronger. Quite some pain in the injection site, a half ass headache, I'm tired, my lymphnodes are not sure what they want to do... I'm generally a bit unwell, but nothing too bad, nothing that should keep anyone from getting the vaccine! I would just advice anyone to schedule in some time to rest in the following day(s).
Wtf... here in Virginia all the doses are being given 6 weeks apart or more, I thought it was because ✨ science ✨but you are saying it’s because politics and dumb?!
Politics has no business overriding science.
My neighbor got the vaccine and is now in the ICU so if people want to take the risk go ahead but no thanks for me I don't want it I'll take my chances!
Astrazeneca released data today to suggest delaying the second dose increases efficacy. A seperate study also released today suggests that antibodies last for at least 6 months.
These guys are Bill Gates sell-outs. These shots don't evwn come close to being what the term vaccine means. He just spoke false information about the serums they are using. There are many other scientis who haven't sold out who are giving clear information concise information without the false narrative.
I'm hearing anecdotal accounts that the second dose is not as well tolerated as the first dose. I wonder if the spacing between doses might also have an effect on a more intense reaction to the second dose.
Great... Sounds like we're just a hop - step & jump from the zombie apocalypse.
I thought one dose was the same as no dose...
Thank you for that info. Another question, what are the possible side effects, short and long term?
Still a good year away from achieving herd immunity
The guy playing plague inc right now must be laughing like a villain