We Found a Bunch of New Eye Color Genes | SciShow News

1 411 Shikime 142 mijë

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This week, scientists have managed to make tear gland organoids that cry, and have also found a bunch of new genes involved in eye color!
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Tear Ducts
Paper: www.cell.com/cell-stem-cell/fulltext/S1934-5909(21)00075-8
Press release 1: www.eurekalert.org/emb_releases/2021-03/cp-tgi031121.php
Press release 2: www.eurekalert.org/emb_releases/2021-03/hi-cht031121.php
Sjogren’s: www.sjogrens.org/understanding-sjogrens ogren
Eye Color
Original paper: advances.sciencemag.org/content/7/11/eabd1239
Press release: www.eurekalert.org/pub_releases/2021-03/kcl-5ng031121.php
Mendelian trait: www.nature.com/articles/jhg2010126
Image Sources:


  1. SciShow
    23 ditë më parë

    SciShow is supported by Brilliant.org. Go to Brilliant.org/SciShow​ to get 20% off of an annual Premium subscription.

    1. Sarvajit Karanth
      Sarvajit Karanth
      21 ditë më parë

      I have brilliant already so what should I do?

    2. Jean Paul Betancourt
      Jean Paul Betancourt
      21 ditë më parë


    3. Hope Franklin
      Hope Franklin
      23 ditë më parë

      Can you do a video of indigestion please, if you have tho that's ok too

    4. Jalen McCollum
      Jalen McCollum
      23 ditë më parë

      So,...what you are saying is: Candy-colored eyes are possible?

    5. Josh
      23 ditë më parë

      i do enjoy brilliant, when I need a subscription I will use your link

  2. Glasses&Tea
    34 minuta më parë

    My mom has green eyes and had blonde when she was a kid, now brown hair. My dad brown eyes and blonde hair growing up, now brown. I have eyes that go to from dark brown to green with blonde hair that's turning red.

  3. Julia Connell
    Julia Connell
    Ditë më parë

    As a person whose eye course is hmm *complicated* - I really appreciate the simple acknowledgement that eyes are MORE than brown, blue, green etc - mine *CHANGE* - sometimes they're grayish, greenish (with clothes & makeup can enhance this) - blueish/brownish - known this since I was a kid - (now in my late 40s) - when it comes up with passport applications - never ever know what to put down

  4. Noobmaster69
    3 ditë më parë

    I have brown eyes but I’m told by a lot of people that when the light catches my eyes the color of my eyes look like a red brown, I think it’s pretty dope that the color of my eyes are slightly red, my mom has hazel eyes and my dad has green eyes btw, my older brothers eyes change from grey, blue, to green under different lightings (and I mean really vibrant ocean blue and like forest green)and my nana also has one blue eye and one brown.

  5. ShWeJaPa
    3 ditë më parë


  6. Keith M
    Keith M
    4 ditë më parë

    Anyone who has blue eyes is evil. Just ask msn and cnn 🤣

  7. B
    5 ditë më parë

    For the algorithm.

  8. Clyde Craft
    Clyde Craft
    11 ditë më parë

    I have grey eyes, i read thats such a low % that we dont even know the exact amount, just that its below 1%

  9. Chandra Wijaya
    Chandra Wijaya
    12 ditë më parë


  10. DustyTheDog
    13 ditë më parë

    I have blue eyes, and so does almost everyone in my family. My great grandfather on my dad's side had six boys, all of which have blue eyes. My mom's parent's have blue eyes, and so does she and her 2 sisters. My older sister(who has a different dad than me and my younger sister) has green eyes, while my younger sister and I(who share both parents) have blue eyes. The only people without blue eyes are the children of the couples where my family member married someone without blue eyes. We also have an astounding number of lefty's in my family. We think my great grandfather and grandfather on my dad's side were born lefty, but taught to be right handed because in the early 1900's and before it was seen as evil and part of the devil to be left-handed. Grandpa says he can't remember being taught to be right handed, but he feels more comfortable using his left for most things. I am completely ambidextrous. I can do fine motor movements with equal skill and comfort with both hands. My great grandfather died in 2016, before I really took interest in my genealogy, so I only have some brief stories of what early life was like for him in the Depression and WW2. Great grandpa had a Purple Heart and I was more interested in that growing up. I never got to ask him about which hand he prefers to use. It was his left side that was injured in WW2, so he had to use his right after that. The point of this spiel: genetics are weird.

  11. Lauren Bobo
    Lauren Bobo
    13 ditë më parë

    My mom has dark blue/green eyes. Her mom has bright blue eyes. Her father has brown eyes. A few of her grandparents had blue eyes. I’ve always been curious as to why her shade was so much darker than the other blue eyed family members in my family.

  12. Brian Stover
    Brian Stover
    14 ditë më parë

    How about eye color that changes as you age? I grew up with distinctly hazel eyes and now have blue eyes. My blue eyes get duller the older I get, meaning more grey and less blue every year.

  13. Sawsy_Chicken
    15 ditë më parë

    I have central heterochromia. I have grey on my outer ring and a green star burst formation around my pupil.

  14. louve ataky
    louve ataky
    15 ditë më parë

    It's obviously very complicated. For some people, when you look at their eyes you can actually see that it's a mix of different colors, like blue with a yellowish ring, or brown around the pupil and green above, or multiple shades of brown with some redish or honey color. I myself have green-greyish eyes with some yellow on top of the pupil, my mother have sky blue and my father a light shade of brown.

  15. No Bo
    No Bo
    16 ditë më parë

    Has anyone noticed an eye color change, after having the Covid -19 Shot? Like from green to blue.

  16. Zes
    16 ditë më parë

    no such thign as dnax or not, doentt matter

  17. Shirin Chatterjee
    Shirin Chatterjee
    18 ditë më parë

    I like that you include what the broad scope of the research is.

  18. erikk77
    18 ditë më parë

    1:05 "I'll give you something to cry about!"

  19. Sleekoduck
    18 ditë më parë

    I knew the DNA sites needed more work a few years ago. GEDcom said I had green eyes. Mine are amber. Those are both rare colors, but there's a huge difference between the two. I'm glad to hear that they're discovering more alleles.

  20. Megan The Architect Brown
    Megan The Architect Brown
    19 ditë më parë

    The fact that you referenced, "The Fault In Our Stars", made me an even bigger fan of you.

  21. JAYNIE Randolph
    JAYNIE Randolph
    19 ditë më parë

    I have green with a dark ring yellow towards the pupil and a brown spot

  22. Abdul Rasheed K.k Rasheed K.k
    Abdul Rasheed K.k Rasheed K.k
    19 ditë më parë

    ➡️ 18cams.xyz ⤵️ B.e.S.T f'u"l'l D.a.T.i.n.G h.o.T G.i.r.L's -L-o-V-e-S-e-X---❤️😘 ..👍 !💖🖤❤️今後は気をライブ配信の再編ありがとうです!この日のライブ配信は、かならりやばかったですね!1万人を超える人が見ていたもん(笑)やっぱり人参最高!まさかのカメラ切り忘れでやら1かしたのもドキドキでした,. 💖🖤在整個人類歷史上,強者,富人和具有狡猾特質的人捕食部落,氏族,城鎮,城市和鄉村中的弱者,無`'守和貧窮成員。然而,人類的生存意願迫使那些被拒絕,被剝奪或摧毀的基本需求的人們找到了一種生活方式,並繼續將其DNA融入不斷發展的人類社會。. 說到食物,不要以為那些被拒絕的人只吃垃圾。相反,他們學會了在被忽視的肉類和蔬菜中尋找營養。他們學會了清潔,切塊,調味和慢燉慢燉的野菜和肉類,在食品市場上被忽略的部分家用蔬菜和肉類,並且學會了使用芳香的木煙(如山核桃,山核桃和豆科灌木 來調味g食物煮的時候

  23. Nery Hs
    Nery Hs
    19 ditë më parë

    hank mentioning the fault in our stars was so cute

  24. James
    19 ditë më parë

    so humanoids incoming?

  25. Hélène Honsbein
    Hélène Honsbein
    19 ditë më parë

    3:40 Those are some seriously beautiful eyes.

  26. Ben McReynolds
    Ben McReynolds
    19 ditë më parë

    Isn't it cool that anytime you're depressed and need cheering up☝️ you can think about how everytime we think we learn something... We look at it further and find more and more layers of the onion to peal through to get to even more intricate layers of information and knowledge that we will one day learn to harness for our own positive benefits. (Curiousity for me doesn't kill the cat, it's the only thing that keeps it alive matter a fact. )

  27. Gisha Gesta
    Gisha Gesta
    19 ditë më parë

    Fellow Blue Eyes gang, where you at?

  28. Zeppelin Estrada
    Zeppelin Estrada
    19 ditë më parë

    My eyes are light brown, but they occasionally look green, I don't know why but I would like too

  29. fluteplayer
    20 ditë më parë

    Yeah those punet squares always confused me because my mom has brown eyes and my dad has blue eyes but my eyes are brown around the pupil but blue around the edge, so I got both and that was never an option lol (when I have to fill out forms I just say blue cuz like if my eye is super dilated that’s what color they are)

  30. ChozoSR388
    20 ditë më parë

    So, it IS possible for 2 blue-eyed people to produce offspring with green eyes. Well, that certainly does take some weight off of my shoulders.

  31. LoonyEclipse
    20 ditë më parë

    Was there anything on eye color that changes after childhood? Mine has changed since pregnancy.

  32. Maayan Stern
    Maayan Stern
    20 ditë më parë

    My mom and I both have central heterochromia of the type usually associated with hazel eyes, and I can state that in my family it does look like a simple situation- mother and daughter with hazel eyes and the recessive gene for blue, father and son with blue eyes. It's not. My eyes are amber around the center and green around that, with a thick dark ring around the border. As for why eyes can be several different colors at the same time? Rayleigh scattering.

  33. Norm Zemke
    Norm Zemke
    20 ditë më parë

    At 4:50... "there is always something more to understand"..... Yep! 50 more genes controlling eye color! Who would have thought! Keep the videos coming. They are great!

  34. DexyD20
    21 ditë më parë

    but what about people who say their eye colors change? Is that a thing?

  35. Alexander Of Rhodes
    Alexander Of Rhodes
    21 ditë më parë

    It's so sweet how Hank shouts out his brothers book whenever he can

  36. Gajanan Nigade
    Gajanan Nigade
    21 ditë më parë

    Titanic & fault in our stars? Really??

  37. Roxanne Marius
    Roxanne Marius
    21 ditë më parë

    Maybe an anomaly with tri-colour eyes, blue on the outer edge, green in the center, and flecks of hazel or wheat across the iris. With both parents having deep brown eyes. Early 2000's science class taught me with the classic Pennet square that somebody was cheating. 😅

  38. Kathleen Patricia
    Kathleen Patricia
    21 ditë më parë

    He reminds me of Dr. Stork from The Doctors but with glasses

  39. Bella Dillashaw
    Bella Dillashaw
    21 ditë më parë

    I love scishow so much, it reminds me how much I love science when school gets rough 💞💞

  40. Victor Cavalcanti
    Victor Cavalcanti
    21 ditë më parë

    Would be nice to invite African participants for the eye colour study, since they have the most diverse genetic pool. Also, black people are often disregarded in scientific studies as population samples that aren't specifically about black people characteristics ¯\_(ツ)_/¯

  41. Ermude10
    22 ditë më parë

    I think this is a prime example of that we should be vary of "facts". Not that we should be overly skeptical about established truths, but we shouldn't be dogmatic about anything that involves complex processes and systems. Being aware that most things probably have nuance and non-simple answers is so important for actually understanding the world, problems we encounter, and how we can solve it and what trade-offs we make.

  42. Foster
    22 ditë më parë

    "Fault in our stars, what's that?" I'm sure John and Josh appreciate the plug.

    22 ditë më parë

    my skin pigmentation is darker than my siblings but my eye color is of a lighter shade of brown than my siblings

  44. Elizabeth Barry
    Elizabeth Barry
    22 ditë më parë

    This explains why I have no idea what colour my eyes are. Somewhere in between blue and green but with a light brown tint in the centre

  45. rjr
    22 ditë më parë

    Funny, I don't think my eye color is unique by any means but it's straight up orange. With any real lighting, at the very least, a bright auburn like my hair was growing up. My mom's are the same but everyone else has blue, green, or hazel eyes in our immediate families.

  46. Ivi-Tora Ineru
    Ivi-Tora Ineru
    22 ditë më parë

    Don't forget red, orange, violet and white eyes used to be common colors before the various churches of the middle ages associated those color with "evil" and purged them out the gene pool by shunning or outright killing those poor people.

  47. eAcast55
    22 ditë më parë

    Blonde hair and blue eyes have nothing to do with each other. Blue eyes are euopean neolithic heritage, Blondes existed prolly as Neandertal or Cro Magnon already.

  48. Tara 907
    Tara 907
    22 ditë më parë

    My eyes are dark blue (slightly grey) with a green ring in the center, my husband’s eyes are a green-dominated hazel- our son has eyes very similar to mine....but my daughter has straight GREY eyes. No blue. No green. No brown. Grey. At 2 we still have the hardest time answering if we are asked her eye color. But friends and family we have asked to weigh in all say grey.

  49. Heather Hogan
    Heather Hogan
    22 ditë më parë

    Every member of my family has a different shade of green eyes. I remember learning the overly simplistic blue/brown model and thinking there's got to be a lot more to this!

  50. Ankle Donna
    Ankle Donna
    22 ditë më parë

    As always, the more we learn, the more we find how little we really know, and the more it becomes clear that the highest calling is the search for understanding; every answer found leads to more mysteries to pursue. Boredom is impossible for the inquiring mind.

  51. culwin
    22 ditë më parë

    3Blue1Brown has entered the chat

  52. Roselyn Campisi
    Roselyn Campisi
    22 ditë më parë

    Ok here is something I find funny. My mom had brown eyes. My dad had blue eyes. My husbands mom dad sister brother are all brown eyes. My 2 half brothers are brown eyes. I have 2 children with hazel eyes. My daughter has brown hair and my son has blond hair. What happened here? I have red hair. How did my children get hazel eyes? Shouldn't they have brown like their dad?

  53. Andréa Sharisse
    Andréa Sharisse
    22 ditë më parë

    im black my eyes are dark brown. no depth no nothing just a plain dark brown. kinda wish they were lighter though

  54. Susanne Rack
    Susanne Rack
    22 ditë më parë

    Hi dude. I loved the work. I've been trying to research for a ALfirst video similar to yours that informs the topics in this ALfirst video! 👨‍⚕️ The part at 1:13 is educational. Your explanation totally is similar to the content from this informative health enthusiast Dr. Ethan. Doctor Ethan's tips are helpful and I actually learned a lot for diet. Go check his page out and give the medical student a like over here! ➡️ #DoctorEthanMedLife

  55. Susanne Rack
    Susanne Rack
    22 ditë më parë

    I loved your work! I've been trying to research for an educational vid that really explains the topics in this ALfirst video. 👌Your vid for sure is like the channel of Dr Ethan. Dr's demonstrations are actually helpful and I really learned a lot for my diet. Go see his ALfirst out and give the med student a like! ➡️ #StudentDoctorEthan

  56. Susanne Rack
    Susanne Rack
    22 ditë më parë

    Your vid was so instructional. I have been trying to research for a ALfirst video similar to yours that informs the stuff in this video. The explanation at 1:24 is smart. Your explanation really reminds me of the content of Dr. Ethan. Ethan's explanations are useful and he actually helped me a lot on my studies! He is an educational med student in Nottingham and he explains medical school! Go check his channel out and give the medical student a subscribe! 👉 #DrEthanHealth

  57. Master NER D
    Master NER D
    22 ditë më parë

    Wake up new eye color just dropped

  58. ZipplyZane
    22 ditë më parë

    Is Pizza John on SciShow a normal thing? I've never noticed it before...

  59. harmonicaveronica
    22 ditë më parë

    Man I was hoping they made them cry by sticking onions in the dish

  60. Jason King
    Jason King
    22 ditë më parë

    All these genes, and eye color doesn't matter?

  61. Kim Bratton
    Kim Bratton
    22 ditë më parë

    I can't get enough of SciShow!

  62. Eva Sartorius
    Eva Sartorius
    22 ditë më parë

    Thanks for this, I have had Sjogrens for over 30 years.

  63. Xero0
    22 ditë më parë

    u should make a video on hair colors! (and plz on ginger hair in detail haha)

  64. Cirrus
    22 ditë më parë

    I always hate when options for eye color don't include colors like hazel, my eyes are are not green, brown, blue, gray, etc and I never know which one to choose

  65. Zin Zevvenneer
    Zin Zevvenneer
    22 ditë më parë

    I had brown eyes but they started turning hazel and green, is that normal?

  66. Austin Hibdon
    Austin Hibdon
    22 ditë më parë

    The most shocking part of this for me was thatice have tears.

  67. Omg Giiirl
    Omg Giiirl
    22 ditë më parë

    You know it would be so crazy if there are many more colors, its just that our receptors aren't evolved enough to percieve them.

  68. mlbh2os211
    22 ditë më parë

    SciShow produces a lot of videos that sometime creeps me out. However the "crying petri dish" tops them all....😲😬

  69. Who Ever
    Who Ever
    22 ditë më parë

    Considering that the pigment part of the eye is muscle tissue, this might explain why some people's eyes can change colors.

  70. nihilsson
    22 ditë më parë

    if Pax6 is a gene why is a model of a protein shown?

  71. My Phone
    My Phone
    22 ditë më parë

    Proud owner of a set of green eyes!

  72. Ky Crush
    Ky Crush
    22 ditë më parë

    Can you do a video about 'limbal rings'? A pigmented line that separates the iris from the sclera, but not everyone has it.

  73. thes7274473
    22 ditë më parë

    How far away are we from growing replacement clitorises and foreskins for victims of genital mutilation?

  74. mhyzon1
    22 ditë më parë

    Cryin’ Organiods sounds like a DEVO tribute band

  75. RustyTube
    22 ditë më parë

    Thanks for the warning that _The Fault In Our Stars_ is a tear jerker. I shall now remove it from my to-read list.

  76. Richard Boyle
    Richard Boyle
    22 ditë më parë

    hank green referencing his brother book love it

  77. Rick Markus
    Rick Markus
    22 ditë më parë

    1:14 'So instead of making an organoid read the fault in our stars' Shameless brotherly promotion =D

  78. Vee Dragon
    Vee Dragon
    22 ditë më parë

    I appreciate the color work on the word SHADES

  79. PAS Ferret
    PAS Ferret
    23 ditë më parë


  80. Richelle G
    Richelle G
    23 ditë më parë

    My eyes change color between brown, green, and gray. Unfortunately, neither of my kids have inherited them.

  81. Neal Hoffman
    Neal Hoffman
    23 ditë më parë

    My mom has dark brown eyes, dad blue. Mine are concentric green hazel brown

  82. League Master gg
    League Master gg
    23 ditë më parë

    4:08 Look, it’s the rare blue eyes white boy!

  83. Kai Lopez
    Kai Lopez
    23 ditë më parë

    Didn't click on this video thinking I might have hope for my sjogrens someday. It's so much more than just dry eyes and mouth, it's dry everything, joint pain, exhaustion, it's a lot.

  84. Jarrett Benning
    Jarrett Benning
    23 ditë më parë

    I never thought eye color was a mendelian trait. Not because I had any particular reason to but I'm pretty sure I was told in high school biology that traits like height and eye color were affected by many genes and that seemed to make sense since we all know that eyes are pretty much like snow flakes in that there are an extremely wide variety.

  85. Abdullah Hajibaba
    Abdullah Hajibaba
    23 ditë më parë

    No music... I liked this!

  86. Travis Collier
    Travis Collier
    23 ditë më parë

    A word of warning... Association studies tend to generate a lot of false positives.

  87. tojioni21
    23 ditë më parë

    This is why I love science so much like nature it always changes

  88. Travis Collier
    Travis Collier
    23 ditë më parë

    "it was the PAX"

  89. I Collect Stories
    I Collect Stories
    23 ditë më parë

    Lo Pan continues his quest for a green-eyed Chinese girl.

  90. Liz Skelton
    Liz Skelton
    23 ditë më parë

    I have blue/green eyes and my husband has brown eyes and both our kids have blue eyes. My son has blue/green eyes. My husband has 5 siblings , out of 6 kids only he and his sister have brown eyes , everyone else has blue.

  91. Lord Odysseus
    Lord Odysseus
    23 ditë më parë

    My dad had hazel eyes. My mom had dark brown eyes. My own eyes are a slightly lighter shade of brown.

  92. lisarmia
    23 ditë më parë

    Yeah, this is what we should be spending research money on, studying tear ducts and eye colors genes, instead of say....cancer, or something.

  93. Accordionbabe
    23 ditë më parë

    Gene's schemes. T-shirt collection is cool! Love the video too.

  94. SkeletoPedia - Anatomy Education
    SkeletoPedia - Anatomy Education
    23 ditë më parë

    Hank makes me cry tears of knowledge ;)

  95. Notch Poodles
    Notch Poodles
    23 ditë më parë

    Lmao he’s out here putting a shameless plug for his brother’s book

  96. Steven Utter
    Steven Utter
    23 ditë më parë

    I got an idea instead of researching how to fix broken tear glands you research how to cure cancer, or heart disease, or obesity, and then we won't need the tear glands anymore anyways .

  97. Zak LeClaire
    Zak LeClaire
    23 ditë më parë

    Well I guess this explains why my eyes are kinda mixed brown with a bit of green, my sisters are light blue, but my parents eyes are dark blue and light green, respectively. Both of my grandpa's had brown eyes but one grandma had blue and the other green.

  98. Luis Guevara
    Luis Guevara
    23 ditë më parë


  99. Ashmeed Mohammed
    Ashmeed Mohammed
    23 ditë më parë

    this revelation of how complext and interlinked genes are for different traits, is why i didnt like crspr. ur sniping genes, but u dont know what exactly they affect for other things.

  100. Ashmeed Mohammed
    Ashmeed Mohammed
    23 ditë më parë

    the world: more research is needed.